Online MoCap Data Coding with Bit Allocation, Rate Control, and Motion-Adaptive Post-Processing

With the advancements in methods for capturing 3D object motion, motion capture (MoCap) data are starting to be used beyond their traditional realm of animation and gaming in areas such as the arts, rehabilitation, automotive industry, remote interactions, and so on. As the amount of MoCap data increases, compression becomes crucial for further expansion and adoption of these technologies. In this paper, we extend our previous work on low-delay MoCap data compression by introducing two improvements. The first improvement is the bit allocation to long-term and short-term reference MoCap frames, which provides a 10-15% reduction in coded bitrate at the same quality. The second improvement is the post-processing in the form of motion-adaptive temporal low-pass filtering, which is able to provide another 9-13%savings in the bitrate. The experimental results also indicate that the proposed online MoCap codec is competitive with several state-of-the-art offline codecs. Overall, the proposed techniques integrate into a highly effective online MoCap codec that is suitable for low-delay applications, whose implementation is provided alongside this paper to aid further research in the field

Carriage of Cytochrome 2C19 Polymorphism Is Associated With Risk of High Post-Treatment Platelet Reactivity on High Maintenance-Dose Clopidogrel of 150 mg/day Results of the ACCEL-DOUBLE (Accelerated Platelet Inhibition by a Double Dose of Clopidogrel According to Gene Polymorphism) Study

ObjectivesThis study sought to determine the impact of gene polymorphisms on platelet reactivity (PR) after clopidogrel 150 mg/day in patients treated with percutaneous coronary intervention (PCI).BackgroundAlthough high maintenance-dose (MD) clopidogrel reduces PR, it is unknown whether gene polymorphisms are related with the risk of high post-treatment PR (HPPR) after high-MD clopidogrel.MethodsWe included mostly patients receiving high-MD clopidogrel after PCI from previously registered Gyeongsang National University Hospital data. A total of 126 PCI-treated patients receiving high-MD clopidogrel were enrolled. Platelet reactivity was assessed with conventional aggregometry and VerifyNow (Accumetrics Inc., San Diego, California) after receiving clopidogrel 150 mg/day for at least 1 month. CYP3A5, CYP2C19, and ABCB1 genotyping was performed. We defined HPPR as 5 μmol/l adenosine diphosphate (ADP)–induced maximal PR (PRmax) >50%.ResultsCYP3A5 and ABCB1 polymorphisms did not influence PR. Carriers of CYP2C19 variant (*2 or *3) (n = 80) had significantly higher 5 and 20 μmol/l ADP-induced PRmax than did noncarriers (n = 46) (40.7 ± 16.8% vs. 30.3 ± 12.6%, p < 0.001; 54.2 ± 16.2% vs. 40.5 ± 15.8%, p < 0.001, respectively). Late PR and VerifyNow results indicated consistently greater measures in carriers versus noncarriers of CYP2C19 variant. All platelet measures proportionally increased according to the number of CYP2C19 variant alleles. Twenty-seven (21.4%) patients met the criteria for HPPR. Prevalence of HPPR was 8.7%, 21.7%, and 50.0% in carriers of 0, 1, and 2 CYP2C19 variant alleles, respectively (p < 0.001). By multivariate analysis, carriage of CYP2C19 variant was a significant predictor of HPPR (odds ratio: 5.525, 95% confidence interval: 1.333 to 23.256, p = 0.018).ConclusionsAmong PCI-treated patients receiving high-MD clopidogrel, carriage of CYP2C19 variant relates to increased PR and predicts risk of HPPR. (Adjunctive Cilostazol Versus High Maintenance-dose ClopidogrEL in Acute Myocardial Infarction [AMI] Patients According to CYP2C19 Polymorphism [ACCELAMI2C19]; NCT00915733; and Comparison of Platelet Inhibition With Adjunctive Cilostazol Versus High Maintenance-Dose Clopidogrel According to Hepatic Cytochrome 2C19 Allele (CYP2C19) Polymorphism [ACCEL2C19]; NCT00891670)

A Case of Spontaneous Coronary Artery Dissection Healed by Medical Treatment: Serial Findings of Coronary Angiography, Intravascular Ultrasound and Multi-Detector Computed Tomography

Spontaneous coronary artery dissection (SCAD) is an uncommon cause of acute coronary syndrome which may be related to lethal condition. Although several modalities including medical therapy have been suggested, agreement on optimal treatment has not yet been determined. We describe a case of SCAD which was presented as ST-segment elevation myocardial infarction, and treated successfully with medical treatment. Coronary angiography, intravascular ultrasound and multi-detector computed tomography showed the serial changes of this disease entity

Examining Television Consumers of Mixed Martial Arts: The Relationship Among Risk Taking, Emotion, Attitude, and Actual Sport-Media-Consumption Behavior

The current study employs the hedonic paradigm model (Hirschman & Holbrook, 1982) to investigate the interceding function of emotions on the relationship between personality (i.e., risk taking) and attitude toward mixed martial arts. This study also examines sport-media (e.g., television) consumption of a nontraditional sport. Structural equation modeling was used to examine the proposed model incorporating risk taking, pleasure, arousal, attitude, and actual consumption behavior. The study found a significant mediation effect of emotion (pleasure and arousal) in the relationship between risk taking and attitude. In addition, attitude showed a direct and significant influence on actual media-consumption behavior. Theoretical and practical implications of the results are discussed, along with future directions for research